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  • PHYSIOLOGY AND PATHOLOGY OF CHLORIDE TRANSPORTERS AND CHANNELS IN THE NERVOUS SYSTEM
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    PHYSIOLOGY AND PATHOLOGY OF CHLORIDE TRANSPORTERS AND CHANNELS IN THE NERVOUS SYSTEM
    F. JAVIER ALVAREZ-LEEFMANS
    The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium acros...

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